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Senior Scientist, Innate Immunity and Metabolism job in Cambridge

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Pfizer jobs
Country:  United States
State:  Massachusetts (MA)
City:  Cambridge

The Internal Medicine Research Unit (IMRU) is committed to finding cures for cardiovascular disease, metabolic diseases and related complications. Our goal is to build a research team of driven scientists focused on developing a deep mechanistic understanding of the metabolic pathways driving Nonalcoholic Steatohepatitis (NASH), cachexia, obesity, diabetes and cardiovascular disease. The aim is to recruit a scientifically and technically strong research scientist proficient in in vivo and in vitro models for metabolic research. The scientific focus of this role is to identify and validate potential targets and pathways critical for the development of NASH and hyperinsulinemia with the goal of developing effective therapies.

  • Apply scientific and technical expertise to drug discovery programs to impact the future of new drug candidate development
  • Conceptualize and design experiments
  • Organize and conduct in vivo/ ex vivo/ in vitro studies independently (including preparation, data collection, interpretation, and presentation)
  • Maintain awareness of scientific and technical developments in field
  • Author manuscripts for quality publications in top-tier journals.
  • Interface with an interdisciplinary team of scientists in the Internal Medicine Research Unit and engage in both target exploration and driving established projects in our portfolio. 
  • Quantify and translate experimental results to advance the understanding of how metabolic pathways and complex physiological systems are altered by diseases and how they respond to therapeutic interventions.
  • Maintenance of laboratory notebook records and adherence to safety policies is strictly required.

  • PhD with a minimum of 2 years of post-doc experience in inflammation research, pharmacology, cell biology, or physiology. 
  • Deep expertise in cell biology with emphasis on inflammation and signaling pathways is required. Experience working with various cell types including inflammatory cells is a plus.
  • Experience in performing in vitro, in vivo and ex vivo experiments
  • A successful track record of scientific achievements through scientific publications and presentations
  • Candidate should be able to review literature to formulate new ideas, and have the ability to work independently as well as with an interdisciplinary team of scientists in a highly collaborative environment.
  • The candidate will have daily interactions with a team of creative and innovative scientists in a supportive environment.  Excellent communication and interpersonal skills are essential. 

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.   Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Other Job Details:
  • Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Position Type:  Full Time
Employer:  Pfizer


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